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Pneumoperitoneum (causes)

AbdomenRadiograph / CT

Free intraperitoneal gas. Most cases reflect a perforated viscus needing surgery; recent surgery and other non-surgical causes must be recognised to avoid unnecessary laparotomy.

Differential

Perforated peptic ulcer

common
  • Free gas tracking to a duodenal/gastric wall defect
  • Periduodenal fluid and fat stranding
  • Acute epigastric peritonitis

Perforated diverticulitis / colonic perforation

common
  • Sigmoid diverticula with pericolic gas and abscess
  • Faecal-loaded colon; left iliac fossa pain

Recent surgery / laparoscopy

common
  • Postoperative context; gas decreasing on serial imaging
  • Expected up to ~1 week post-laparotomy

Bowel perforation from obstruction/ischaemia

less-common
  • Dilated bowel or pneumatosis with portal venous gas
  • Wall non-enhancement

Ruptured pneumatosis / diverticulosis (benign)

rare
  • Pneumatosis cystoides intestinalis without peritonitis
  • Clinically well despite free gas

Thoracic / iatrogenic tracking

rare
  • Barotrauma or recent endoscopy/PEG placement
  • Gas continuity from chest or procedure site

Key discriminators

  • Site of gas and any visible wall defect on CT
  • Recent surgical/procedural history
  • Associated peritonitis vs clinically well
  • Bowel dilatation, pneumatosis or portal venous gas
  • Serial change (postoperative gas resolves)

Work-up / next steps

  1. 1.Erect chest/lateral decubitus radiograph, then CT to localise perforation
  2. 2.Correlate with recent surgery/procedures and clinical state
  3. 3.Urgent surgical review for a perforated viscus
  4. 4.Conservative management only for confidently benign causes

References

  • Radiopaedia: Pneumoperitoneum.
  • Pinto A et al. Errors in imaging of pneumoperitoneum. Radiol Med.

Educational clinical decision support only. This differential does not make a diagnosis, is not a medical device, and must never substitute for interpretation by a qualified radiologist correlated with the full clinical picture and prior imaging.